Spiro [isobenzofuran-1 (3h), 9 '- [9h] xanthen] -3-one, 3', 6 '-dihydroxy-2', 4 ', 5', 7 '-tetraiodo-, what is the chemical structure of Disodium Salt

The full Chinese name of this compound is 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiro [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-keto disodium salt, often referred to as sodium fluorescein. The following describes its chemical structure in the style of ancient proverbs:

This is an organic compound with a unique spiral ring structure. Its core structure is connected by a spiral atom, which cleverly connects the two parts of isobenzofuran and xanthon. In the isobenzofuran fragment, there is a carbonyl group connected to the third position next to the spiral atom, which gives it a specific chemical activity.

Xanthon part, at the key 3 'and 6' check points, each is connected to a hydroxyl group, and the hydroxyl group has active hydrogen, which can participate in many chemical reactions, such as the formation of hydrogen bonds, which affects the solubility of compounds and molecular interactions.

Furthermore, the 2 ', 4', 5 ', and 7' check points are occupied by iodine atoms. Iodine atoms, due to their large atomic radius and special electron cloud structure, endow compounds with unique physical and chemical properties, such as increasing the polarity of molecules, which affects their spectral characteristics.

The whole molecule is in an ionic state and combines with two sodium ions to form its disodium salt form. The presence of sodium ions significantly enhances the solubility of the compound in water, making it more effective in aqueous solution systems. It is often used for tracing and detection in medical diagnostics, analytical chemistry and other fields. This unique structure makes the compound valuable in both scientific research and practical applications.

Spiro [isobenzofuran-1 (3h), 9 '- [9h] xanthen] -3-one, 3', 6 '-dihydroxy-2', 4 ', 5', 7 '-tetraiodo-, what are the main uses of Disodium Salt

This is a substance called 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiro [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-keto disodium salt. Its main uses are quite extensive.

In the field of medical diagnosis, it is often used as a contrast agent. Due to its special chemical structure, it can help to clearly display the shape, structure and blood flow of internal organs and tissues of the human body during X-ray, CT and other imaging examinations. Taking cardiovascular angiography as an example, after injecting this substance, blood vessels can be significantly developed in the image, which can help physicians accurately understand whether there are stenosis, blockage and other lesions in blood vessels, providing a key basis for the diagnosis of cardiovascular diseases.

In scientific research experiments, it also has important value. As a marker, it can label biomolecules. When studying the transportation and localization of specific proteins in cells, this substance is connected to the target protein. With its unique optical or chemical properties, it can track the whereabouts of proteins with the help of microscopes and other equipment, and gain in-depth understanding of cellular physiological processes and pathological mechanisms.

In the field of materials science, it can be used to prepare materials with special optical properties. Due to its iodine and other elements and specific molecular structure, or endowing the material with unique light absorption and emission characteristics, it is used in optical sensors, fluorescent materials, etc., to achieve high sensitivity detection and response to specific substances or physical quantities.

Spiro [isobenzofuran-1 (3h), 9 '- [9h] xanthen] -3-one, 3', 6 '-dihydroxy-2', 4 ', 5', 7 '-tetraiodo-, what are the physical properties of Disodium Salt

This is 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiral [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-keto disodium salt, which has unique physical properties. Looking at its properties, at room temperature, it is mostly in the state of powder, white or near-white, fine and uniform.

When it comes to solubility, this substance exhibits good solubility in water, and can quickly blend with water to form a uniform and stable solution. This property is due to the specific interaction between its molecular structure and water molecules, such as the action of hydrogen bonds, which promotes its dispersion in water. However, in organic solvents such as ethanol and ether, its solubility is significantly inferior, and it is difficult to form a uniform dispersion system due to the difference in the forces between molecules and organic solvents.

Another word, the melting point of this substance is determined experimentally within a certain range. This value is one of its inherent physical properties and is determined by various factors such as intermolecular forces and lattice energy. This melting point value is of great significance for its processing and application under specific conditions. For example, when used in high temperature environments, it is necessary to consider whether its morphology and properties will be changed due to approaching or exceeding the melting point.

As for density, it is also an important physical property. This density value determines its floating state in different media, etc. In the related production and application process, according to this density characteristic, it can be separated and purified by means of sedimentation, centrifugation and other means.

In summary, the physical properties of 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiral [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-keto disodium salt are of crucial guiding value for its application and research in many fields such as chemical industry and medicine.

Spiro [isobenzofuran-1 (3h), 9 '- [9h] xanthen] -3-one, 3', 6 '-dihydroxy-2', 4 ', 5', 7 '-tetraiodo-, what are the synthetic methods of Disodium Salt

This is a method for the synthesis of disodium 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiro [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-one. There are many methods, common ones are based on xanthon and isobenzofuran, which are prepared by halogenation, hydroxylation and salt formation.

First take xanthon tons and halogenate with iodine to obtain 2', 4 ', 5', 7 '-tetraiodoxanthon tons. When halogenating, when controlling the temperature, time and amount of iodine of the reaction, the yield increase rate and the control of side effects. Then, the hydroxyl group is introduced to obtain 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodoxanthon. This step can be achieved by using a specific hydroxylation reagent according to suitable reaction conditions.

Then, 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodoxanthon reacts with isobenzofuran to form a spiral [isobenzofuran-1 (3H), 9 '- [9H] ton] -3-one structure. In the spiral ring formation reaction, a suitable catalyst and solvent need to be selected to promote the anterograde reaction. At the end of

, the product is reacted with a sodium source to form disodium 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiro [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-one. When forming a salt, attention should be paid to the type, dosage and reaction environment of the sodium source to obtain a high-purity product.

During the synthesis process, each step of the reaction requires precise control of the reaction conditions, such as temperature, time, and the proportion of reactants, and appropriate separation and purification methods are required to extract the purity and yield of the product. The product of each step should be analyzed and identified in detail to ensure that the reaction proceeds as expected.

Spiro [isobenzofuran-1 (3h), 9 '- [9h] xanthen] -3-one, 3', 6 '-dihydroxy-2', 4 ', 5', 7 '-tetraiodo-, Disodium Salt What are the precautions during use?

This is called 3 ', 6' -dihydroxy-2 ', 4', 5 ', 7' -tetraiodospiral [isobenzofuran-1 (3H), 9 '- [9H] xanthon] -3-keto disodium salt. When using, pay attention to many matters.

First, this agent has specific chemical properties, mixing with other substances, or biochemical reactions, resulting in changes in properties. Therefore, when using it, it must be carefully reviewed for compatibility with other agents or substances used, and must not be mixed rashly.

Second, it may have the risk of sensitization to the human body. Before use, check whether you are allergic. Try a small amount first to see if there is any discomfort. If you feel itchy, red and swollen skin, or allergic symptoms such as poor breathing, stop using it immediately and seek medical assistance.

Third, the preservation of this agent is also a priority. It needs to be placed in a dry, cool and ventilated place to avoid direct sunlight. If it is not well preserved, it will deteriorate, not only will the effect be greatly reduced, but also harmful things will be produced.

Fourth, those who use it should be aware of its usage and dosage, and should not change it. Excessive use may cause adverse consequences, such as drug poisoning; if the dosage is insufficient, it will be difficult to achieve the expected effect. Be sure to follow the doctor's instructions or instructions for use, and use it accurately.

Fifth, during use, pay attention to observe its effect and reaction. If the symptoms do not decrease after use, or there are new reactions, seek medical advice quickly, and do not delay. In this way, it can be used safely and achieve the desired purpose.