Tert-butyl 4-(4-iodo-1h-pyrazol-1-yl)piperidine-1-carboxylate

The chemical structure of tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester is the structure of a specific compound in the field of organic chemistry. The structure of this compound is composed of several parts.
The tert-butyl and tert-butyl groups are a group with a specific spatial configuration and electronic effect. They are formed by connecting three methyl groups to the same carbon atom and form an umbrella, which has a great influence on the spatial resistance and physicochemical properties of the whole compound.
4- (4-iodine-1H-pyrazole-1-yl) part, the pyrazole ring is a five-membered nitrogen-containing heterocycle, which has aromatic properties and endows the compound with unique electron cloud distribution and reactivity. The introduction of the 4-position iodine atom significantly changes the electron density around the pyrazole ring due to the large atomic radius and strong electronegativity of the iodine atom, which in turn affects the interaction of this part with other groups. The 1-position of the pyrazole ring is connected to the piperidine ring, which is a six-membered nitrogen-containing saturated heterocycle with certain flexibility and alkalinity. It plays an important role in the overall properties of the compound.
The part of piperidine-1-carboxylic acid ester, the carboxylic acid ester group endows the compound with certain polarity and reactivity, and can participate in a variety of organic reactions. And this ester group is connected to the piperidine ring and works synergistically with other parts of the molecule to affect the solubility, stability and biological activity of the compound.
In summary, the chemical structure of tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester, and the interaction of each part jointly determines the unique properties and potential applications of this compound in organic synthesis, medicinal chemistry and other fields.

Tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of characteristic drug molecules. Taking the development of new antidepressant drugs as an example, because of their unique structure, they can precisely interact with specific neurotransmitter receptors. By introducing this compound, the molecular structure of the drug can be ingeniously modified to improve the affinity and selectivity of the receptor, thereby optimizing the drug efficacy.
In the field of materials science, it also shows important value. In the process of creating some organic optoelectronic materials, tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylate can be integrated into the material system as a functional structural unit. Due to its special electronic structure, it can adjust the charge transport properties and optical properties of the material, helping to prepare organic Light Emitting Diode (OLED) materials with high luminous efficiency and long service life, or organic semiconductor materials with excellent carrier mobility.
In the field of organic synthetic chemistry, it is a powerful tool for constructing complex organic molecules. With its reactive activity check point, such as the activity of iodine atom and pyrazolyl, piperidine ring, it can be skillfully spliced with other organic fragments through a variety of classical organic reactions, such as coupling reaction, cyclization reaction, etc., to achieve the efficient construction of complex organic skeleton, laying the foundation for the synthesis of organic compounds with novel structures, potential biological activities or material properties.

To prepare tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester, the following method can be used.
First, appropriate starting materials, such as compounds containing piperidine structure and reagents containing 4-iodine-1H-pyrazole structure, are used under suitable reaction conditions. Usually, a suitable solvent needs to be selected so that the raw materials can be uniformly dispersed to promote the reaction. If a non-protic solvent is selected, such as N, N-dimethylformamide (DMF), it can dissolve a variety of organic compounds and has a stable effect on the ionic intermediates of the reaction system, which is conducive to the reaction.
Then a suitable base needs to be added. The function of the base is to promote the breaking and formation of chemical bonds in the reaction, such as potassium carbonate, which is moderately basic and can capture protons at specific locations in the reactants, initiate nucleophilic substitution and other reaction steps, and promote the formation of tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylate.
The reaction temperature is also a key factor. The raw materials can be contacted with each other at a lower temperature to initially react, and then the temperature can be appropriately increased according to the reaction process to speed up the reaction rate. However, the temperature should not be too high, otherwise it may cause more side reactions and affect the purity and yield of the product.
After the reaction is completed, it often needs to go through post-treatment steps. The reaction solution can be diluted with water first, and then extracted with an organic solvent to transfer the product to the organic phase. After drying, concentration and other operations, the product is initially separated. The high purity tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylate was obtained by column chromatography.

Tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester, this is an organic compound. Its physical properties are quite critical and have a great impact on its performance in various chemical processes and applications.
First, the appearance is usually presented in solid form. The specific appearance may vary due to purity and preparation process, or it is a white to light yellow crystalline powder with fine and uniform texture.
Melting point is one of the important physical properties. The melting point of the compound has been experimentally determined to be in a specific range, and this value can be used for identification and purity detection. Under the given pressure conditions, the melting point is relatively fixed. If impurities are mixed, the melting point may decrease and the melting range becomes wider.
In terms of solubility, organic solvents exhibit different solubility characteristics. Among common organic solvents, such as dichloromethane and chloroform, it has good solubility and can quickly disperse and dissolve to form a uniform solution. This characteristic provides a homogeneous environment for the reaction in organic synthesis, which is conducive to the full progress of the reaction. However, in water, its solubility is poor. Due to the large proportion of hydrophobic groups in the molecular structure, the force between water molecules is weak and it is difficult to dissolve in water.
Density cannot be ignored. The density of this substance has a specific value. Although it is not significantly different from the density of common solvents and reactants, when it comes to phase separation, mixing, etc., the density factor needs to be taken into account, which is related to the stratification of the reaction system and the degree of uniformity of mixing.
In terms of stability, the compound is relatively stable at room temperature and pressure. However, in high temperature, strong light or in a specific chemical environment, the stability may be affected. For example, in case of strong oxidants, strong acids, and strong bases, some chemical bonds in the molecular structure may break or rearrange, resulting in changes in chemical properties.
These physical properties are closely related and affect each other. Appearance is closely related to solubility, and the solid form determines the initial state of dissolution. Melting point and stability also affect each other. When the high temperature approaches the melting point, the stability decreases. Understanding these physical properties is crucial for the compound's applications in organic synthesis, drug development, and other fields.

Now there is tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester, want to know its market price range. However, the price in the market often changes for many reasons, and it is difficult to determine its price.
The price of all kinds of materials in the past, or due to different origins, their quality is different, and the price is also different. If the product is produced in a good place, the quality is high and the quantity is abundant, and the price is slightly flat; if the product is remote and difficult to harvest, the price may be high.
And depending on the supply and demand situation, it also affects its price. If people ask for this product more often, and it is used in medicine, stone, and chemical industries, and the demand is greater than the supply, the price will increase; on the contrary, if the supply exceeds the demand, the price may drop.
And the business skills of merchants are also related to the price. The price of various merchants may be different due to the different fees of transporters and the consumption of storage. Or there is a promotion, and the price also fluctuates.
To sum up, the price of tert-butyl 4- (4-iodine-1H-pyrazole-1-yl) piperidine-1-carboxylic acid ester is difficult to give the exact range directly. It is necessary to observe the situation in detail in the market to know its approximate price.