Tetraiodothyronine
Iodobenzene

Tetraiodothyronine

Fengxi Chemical

Specifications

HS Code

549111

Chemical Formula C15H11I4NO4
Molar Mass 776.87 g/mol
Appearance White to off - white crystalline powder
Solubility In Water Poorly soluble
Melting Point ~150 - 156 °C
Isomerism Exists as L - and D - isomers, with L - thyroxine being the physiologically active form
Biological Role A major thyroid hormone that regulates metabolism, growth, and development
Synthesis Site Produced in the thyroid gland
Mode Of Action Binds to nuclear receptors to regulate gene expression
Transport In Blood Bound to plasma proteins like thyroxine - binding globulin
Name Tetraiodothyronine
Chemical Formula C15H11I4NO4
Molar Mass 776.87 g/mol
Also Known As Thyroxine (T4)
Biological Role Regulates metabolism
Produced In Thyroid gland
Solubility Poorly soluble in water
Transport In Blood Bound to plasma proteins
Activation Converted to triiodothyronine (T3)
Regulation Controlled by hypothalamic - pituitary - thyroid axis
Physiological Effects Affects growth, development, energy utilization
Chemical Formula C15H11I4NO4
Molar Mass 776.87 g/mol
Other Name thyroxine
Type hormone
Produced By thyroid gland
Role regulates metabolism
Solubility poorly soluble in water
Transport In Blood bound to proteins
Synthesis from tyrosine and iodine
Isomerism has optical isomers
Regulation controlled by hypothalamus and pituitary
Chemical Formula C15H11I4NO4
Molar Mass 776.87 g/mol
Other Name thyroxine
Produced In thyroid gland
Role regulates metabolism
Solubility poorly soluble in water
Storage Form bound to plasma proteins
Biosynthesis Precursor tyrosine
Physiological Effect increases basal metabolic rate
Packing & Storage
Packing Tetraiodothyronine in vial packaging, containing 5 grams of the chemical.
Storage Tetraiodothyronine, also known as thyroxine (T4), is typically stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly - sealed container to prevent moisture absorption and degradation. Since it's a hormone - related chemical, proper storage helps maintain its stability and biological activity, ensuring its effectiveness in relevant applications, whether in medical or research settings.
Shipping Tetraiodothyronine, a chemical, is shipped with strict adherence to safety regulations. It's packaged securely in specialized containers to prevent leakage, transported by carriers licensed for handling such substances.
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Tetraiodothyronine Tetraiodothyronine Tetraiodothyronine
General Information
Frequently Asked Questions
What is Tetraiodothyronine?
Tetraiodothyronine is an important hormone secreted by the thyroid gland, commonly known as thyroxine. It plays a key regulatory role in the physiological processes of human metabolism, growth and development.
The thyroid hormones produced by the thyroid gland mainly contain tetraiodothyronine (T4) and triiodothyronine (T3). T4 is named after its molecular structure with tetraiodine. Thyroid follicular epithelial cells first synthesize thyroglobulin containing iodized tyrosine residues, and then undergo a series of subtle biochemical reactions, T4 is formed and stored in the follicle cavity. When the body needs it, T4 is released from the thyroid gland into the blood, mostly combined with plasma proteins, and only a small amount is free.
Free T4 has biological activity, can cross the cell membrane, enter the target cell and bind to the heterosexual receptor in the nucleus, regulate gene transcription, and then affect the process of protein synthesis and cell metabolism. In terms of metabolism, T4 can increase the oxygen consumption rate of most tissues, improve the basal metabolic rate, and release energy to maintain body temperature and meet the needs of body activities. Such as promoting the metabolism of sugar, fat and protein, accelerating the absorption and utilization of glucose, enhancing lipolysis and fatty acid oxidation, and also affecting the synthesis and decomposition of proteins.
is related to growth and development, and T4 is particularly important for nervous system and bone development. In the embryonic stage and infancy, if the secretion of T4 is insufficient, it can cause growth retardation, intellectual development impairment, and lead to nerds. Adults if the secretion of T4 is unbalanced, various diseases also occur. Excessive secretion, showing hyperthyroidism, with fear of heat and sweating, palpitation and trembling, eating more and losing weight, etc.; too little secretion, it is hypothyroidism, see cold fatigue, drowsiness and edema, weight gain, etc.
Therefore, tetraiodothyronine plays an indispensable role in the maintenance and balance of human physiological functions. The regulation of its secretion and related physiological mechanisms have always been the focus of research in the fields of medicine and biology.
What is Tetraiodothyronine?
Tetraiodothyronine, that is, thyroxine, is the most important factor in the human body and is related to all kinds of physiological abilities.
First, it is related to growth and development. In childhood, it is the key to physical and intellectual growth. If the child's body is deficient in this element, growth retardation, short stature, intelligence is also hindered, and it becomes a disease of childhood. Because it has the power to promote bone growth and nervous system development, the proliferation and differentiation of bone growth plates, and the proliferation, migration and differentiation of nerve cells in the nervous system all depend on its help.
Second, regulate metabolism. It can increase basal metabolic rate, increase tissue oxygen consumption and calorie production. It can accelerate the metabolism of sugar, fat and protein. In sugar metabolism, it not only promotes the absorption and utilization of sugar, but also causes glycogen decomposition, which affects the rise and fall of blood sugar. In fat metabolism, it accelerates its decomposition and oxidation, and regulates blood lipid levels. In protein metabolism, when the amount is normal, it promotes its synthesis; when the excess is excessive, it promotes its decomposition.
Third, it also has an effect on the nervous system. Can improve the excitability of the nervous system. Adults who have too much thyroxine often experience restlessness, insomnia and dreaminess; if they are insufficient, it is easy to cause listlessness, lethargy, etc. And it also affects the cardiovascular system, which can accelerate the heart rate and increase the cardiac output. If the secretion is abnormal, cardiovascular diseases or health.
Fourth, in the digestive system, it can increase gastrointestinal peristalsis and promote digestive secretion. If thyroxine secretion is abnormal, digestive function is also implicated, or see hyperappetite but weight loss, or see loss of appetite, abdominal distension and constipation.
Tetraiodothyronine plays an indispensable role in the maintenance of human physiology and the anterograde of growth and development. Its secretion is slightly abnormal, and various diseases may follow.
What are the applicable populations of Tetraiodothyronine?
Tetraiodothyronine, or thyroxine, is related to the regulation of many functions of the human body, and it is suitable for a wide range of people.
In people with hypothyroidism, this is an important treatment drug. Lack of thyroxine secretion can cause metabolic slowdown, such as chills, fatigue, drowsiness, weight gain, constipation and other symptoms. Such patients need to supplement tetraiodothyronine exogenously to restore the normal level of thyroid hormones and return the body's metabolism to normal track.
In addition, some patients with goiter may also be applicable. The causes of goiter are diverse. If the thyroid gland is enlarged due to insufficient synthesis of thyroid hormone and the body compensates for it, supplementation of tetraiodothyronine can inhibit the secretion of thyroid-stimulating hormone in the anterior pituitary gland, so that the goiter can be relieved.
In some special physiological periods, such as pregnancy, women's demand for thyroid hormones increases. If the thyroid gland function is insufficient, or affects the development of the fetal nervous system, it is crucial to supplement tetraiodothyronine in a timely manner to protect the health of mothers and babies.
In addition, patients with thyroid cancer often need to take tetraiodothyronine after surgery. One is to supplement the hormone deficiency caused by surgical removal of the thyroid gland, and the other is to inhibit the secretion of thyroid-stimulating hormone to prevent the recurrence of thyroid cancer.
However, the medication must follow the doctor's advice, and the dose must not be increased or decreased by yourself to avoid hyperthyroidism or other adverse reactions.
What are the side effects of Tetraiodothyronine?
Tetraiodothyronine, or thyroxine, is one of the important hormones secreted by the human thyroid gland. It plays an indispensable role in many key physiological processes such as metabolism, growth and development. However, if its level is abnormal, it will also cause many adverse reactions, which will adversely affect human health.
Excessive thyroxine secretion can cause hyperthyroidism. Patients often feel flustered, just like a deer bumping around, the heart rate is greatly accelerated, and it is far beyond normal when resting. And it is very easy to be irritable, the mood swings like a choppy wave, and it is difficult to control it. The body's metabolism is like a train out of control, accelerating sharply. Although the amount of food is increased, the weight does not increase but decreases, and the muscles feel weak. Sweating profusely and being afraid of heat, even in a cool environment, it often sweats profusely, as if in a hot summer.
And too little thyroid hormone secretion will cause hypothyroidism. At this time, the patient's metabolism is stuck in a quagmire, which slows down significantly. The body lacks heat production, so it is afraid of cold. Even if you add clothes and quilts, you still feel that the chill is difficult to disappear. The spirit is sluggish, drowsy all day, and the thinking becomes sluggish, as if the brain is malfunctioning. The skin becomes rough and dry, just like dry and cracked land, and the hair is easy to fall out. There may also be weight gain, even if the diet has not changed, the weight quietly rises. In addition, female patients may experience symptoms of menstrual disorders, which have adverse effects on the reproductive system.
In summary, although tetraiodothyronine is an essential hormone for the human body, its level must be maintained within the normal range, otherwise, whether it is too high or too low, it will bring many negative effects to the human body, affecting the quality of life and physical health.
How is Tetraiodothyronine used correctly?
Tetraiodothyronine, or thyroxine, is a key hormone secreted by the human thyroid gland and plays a pivotal role in regulating metabolism, growth and development and many other physiological processes. To use this substance correctly, follow the following guidelines:
First medical guidance. This is a medicinal substance, and it should not be used without the diagnosis and prescription of a professional doctor. The doctor will accurately weigh whether it is suitable and the appropriate dose according to the specific symptoms and physical conditions of the individual, such as age, weight, existing diseases and other factors. For example, patients with hypothyroidism need to take drugs containing tetraiodothyronine regularly and quantitatively according to the doctor's instructions to supplement the lack of hormones in the body and maintain normal physiological functions.
Strictly control the dose. The dose is very important, and excessive or insufficient dosage can lead to adverse consequences. If the dose is too large, or the symptoms of hyperthyroidism, such as palpitations, sweating, weight loss, emotional irritability, etc.; if the dose is not enough, it will not be able to effectively improve the hypothyroidism and affect the recovery of the body. Therefore, it is necessary to strictly follow the dose prescribed by the doctor, and should not be increased or decreased at will.
Pay attention to the time and method of medication. It is usually recommended to take it at a fixed time every day to maintain the stability of the drug concentration in the body. It is common to take it on an empty stomach in the morning, and at a certain interval with other drugs to avoid interaction affecting the efficacy. If it is used with calcium, iron, etc., it should be monitored closely for several hours.
< br Go to the hospital regularly to test thyroid function indicators, such as thyroid stimulating hormone (TSH), free thyroxine (FT4), etc., so that the doctor can adjust the treatment plan in a timely manner according to the test results.
Pay attention to adverse reactions. During the medication process, if there are symptoms such as allergic reactions, such as rash and itching; or cardiovascular abnormalities, such as palpitation and chest pain, the doctor should be informed immediately so that timely treatment can be handled.
In short, the correct use of tetraiodothyronine requires the guidance of professional medical personnel, strict follow the doctor's instructions, and close attention to physical reactions and various indicators to ensure the safety and effectiveness of the medication.